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Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer

✍ Scribed by Hsien-yu Wang; Zhiyong Cheng; Craig C. Malbon

Book ID
117467610
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
455 KB
Volume
191
Category
Article
ISSN
0304-3835

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## Abstract The mitogen‐activated protein kinase phosphatase‐1, MKP‐1 (CL100) is involved in inactivation of MAP‐kinase pathways, regulation of stress‐responses and suppression of apoptosis. We investigated expression of MKP‐1 in 90 cases of primary ovarian tumors, 11 normal ovaries as well as 4 ov