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Catalyst Free Indirect Friedländer Synthesis of Substituted Quinolines from Alcohols in PEG-400

✍ Scribed by Fang-Wen Wu; Rei-Sheu Hou; Huey-Min Wang; Iou-Jiun Kang; Ling-Ching Chen


Book ID
112120309
Publisher
Chinese Electronic Periodical Services
Year
2012
Tongue
English
Weight
531 KB
Volume
59
Category
Article
ISSN
0009-4536

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Poly-substituted quinolines were synthesized in the presence of a catalytic amount of dodecylphosphonic acid (DPA) in aqueous media and solvent-free conditions. The reactions proceed very well under relatively mild conditions, and DPA can be recycled.

Friedländer synthesis of poly-substitute
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