✦ LIBER ✦

Cartilage tissue regeneration from bone marrow cells by RWV bioreactor using collagen sponge scaffold

✍ Scribed by Yoshimi Ohyabu; Junzo Tanaka; Yoshito Ikada; Toshimasa Uemura

Book ID: 103847480
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 561 KB
Volume: 29
Category: Article
ISSN: 0928-4931
DOI: 10.1016/j.msec.2008.09.029

No coin nor oath required. For personal study only.

✦ Synopsis

Three dimensional culture techniques have attracted much attention in the field of tissue engineering. Among them, the RWV (rotating wall vessel) bioreactor, which simulates a microgravity environment for cells, is becoming recognized as a useful tool for several kinds of the cells for tissue regeneration such as chondrocytes, osteoblasts etc. In this paper, we report successful control of the cartilage tissue shape from rabbit bone marrow cells by RWV bioreactor using a collagen sponge scaffold. Moreover, the used scaffold was proved to enhance the glycosaminoglycan (GAG) content and strengthened the compression strength of the product, which reached 0.9 MPa in only one-week RWV culture. The usage of a collagen sponge scaffold shortened the necessary culture period for tissue transplantation.

📜 SIMILAR VOLUMES

Cartilaginous tissue formation from bone

Cartilaginous tissue formation from bone marrow cells using rotating wall vessel (RWV) bioreactor

✍ Yoshimi Ohyabu; Naoko Kida; Hiroko Kojima; Tetsushi Taguchi; Junzo Tanaka; Toshi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 316 KB

## Abstract This is the first successful report of the rapid regeneration of three‐dimensional large and homogeneous cartilaginous tissue from rabbit bone marrow cells without a scaffold using a rotating wall vessel (RWV) bioreactor, which simulates a microgravity environment for cells. Bone marrow

Bone and cartilage tissue constructs gro

Bone and cartilage tissue constructs grown using human bone marrow stromal cells, silk scaffolds and rotating bioreactors

✍ Darja Marolt; Alexander Augst; Lisa E. Freed; Charu Vepari; Robert Fajardo; Nipu 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 440 KB

Meniscal regeneration using tissue engin

Meniscal regeneration using tissue engineering with a scaffold derived from a rat meniscus and mesenchymal stromal cells derived from rat bone marrow

✍ Takuma Yamasaki; Masataka Deie; Rikuo Shinomiya; Yasunori Izuta; Yuji Yasunaga; 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 419 KB 👁 1 views

## Abstract The purpose of this study was to regenerate a meniscus using a scaffold from a normal meniscus and mesenchymal stromal cells derived from bone marrow (BM‐MSCs). Thirty Sprague‐Dawley rat menisci were excised and freeze‐thawed three times with liquid nitrogen to kill the original menisca

Transplantation of Meniscus Regenerated

Transplantation of Meniscus Regenerated by Tissue Engineering With a Scaffold Derived From a Rat Meniscus and Mesenchymal Stromal Cells Derived From Rat Bone Marrow

✍ Takuma Yamasaki; Masataka Deie; Rikuo Shinomiya; Yuji Yasunaga; Shinobu Yanada; 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 408 KB