Cartilage-derived morphogenetic protein-1 and -2 are endogenously expressed in healthy and osteoarthritic human articular chondrocytes and stimulate matrix synthesis
β Scribed by K. Bobacz; R. Gruber; A. Soleiman; W.B. Graninger; F.P. Luyten; L. Erlacher
- Book ID
- 114476345
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 351 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1063-4584
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## Abstract ## Objective Bone morphogenetic protein (BMP) and transforming growth factor Ξ² (TGFΞ²) are potent anabolic factors in adult articular chondrocytes. In this study, we investigated whether intracellular inhibitors of BMP and TGFΞ² signaling, inhibitory Smad6 (IβSmad6) and IβSmad7, are expr
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