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Cardiovascular Actions of Some Simple Nucleic Acid Derivatives

✍ Scribed by Sydow, Virginia ;Ahlquist, Raymond P.


Publisher
Elsevier
Year
1954
Weight
464 KB
Volume
43
Category
Article
ISSN
0095-9553

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Nucleic acid-derived drugs exhibit both chemical and physical instability. This mini-review focuses on the prevalent hydrolytic and oxidative pathways of chemical degradation as they are affected by various endogenous (primary structure, chemical modifications in bases, sugars and phosphate residues