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Carcinoembryonic antigen (CEA) presentation and specific T cell-priming by human dendritic cells transfected with CEA-mRNA

✍ Scribed by E Eppler; H Hörig; H.L Kaufman; P Groscurth; L Filgueira


Book ID
117657439
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
423 KB
Volume
38
Category
Article
ISSN
0959-8049

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The application of dendritic cells (DC) to the active immunotherapy of cancer currently relies on the generation of potent DC capable of presenting tumor antigens such as carcinoembryonic antigen (CEA). It is unknown whether the T cells of patients with advanced malignancies can be reliably stimulat