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In vitro induction of carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes by dendritic cells transduced with recombinant adenoviruses

โœ Scribed by Hyun-Il Cho; Hye-Jin Kim; Seoug-Taek Oh; Tai-Gyu Kim


Book ID
117431853
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
383 KB
Volume
22
Category
Article
ISSN
0264-410X

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The application of dendritic cells (DC) to the active immunotherapy of cancer currently relies on the generation of potent DC capable of presenting tumor antigens such as carcinoembryonic antigen (CEA). It is unknown whether the T cells of patients with advanced malignancies can be reliably stimulat