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Carbonic Anhydrase Inhibitors. DNA Cloning, Characterization, and Inhibition Studies of the Human Secretory Isoform VI, a New Target for Sulfonamide and Sulfamate Inhibitors

✍ Scribed by Nishimori, Isao; Minakuchi, Tomoko; Onishi, Saburo; Vullo, Daniela; Scozzafava, Andrea; Supuran, Claudiu T.


Book ID
120272192
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
250 KB
Volume
50
Category
Article
ISSN
0022-2623

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Carbonic anhydrase inhibitors. Inhibitio
✍ Anthony Bertucci; Alessio Innocenti; Andrea Scozzafava; Sylvie TambuttΓ©; Didier πŸ“‚ Article πŸ“… 2011 πŸ› Elsevier Science 🌐 English βš– 211 KB

The catalytic activity and the inhibition of a new coral carbonic anhydrase (CA, EC 4.2.1.1), from the scleractinian coral Stylophora pistillata, STPCA-2, has been investigated. STPCA-2 has high catalytic activity for the physiological reaction being less sensitive to anion and sulfonamide inhibitor