## Abstract Carbonic anhydrases (CAs, EC 4.2.1.1) are a family of enzymes widespread in all life kingdoms. In mammals, isozyme CA IX is highly overexpressed in many cancer types being present in few normal tissues. Its expression is strongly induced by hypoxia present in many tumors, being regulate
✦ LIBER ✦
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides—a new target for the design of antitumor and antiglaucoma drugs?
✍ Scribed by Daniela Vullo; Alessio Innocenti; Isao Nishimori; Jaromı́r Pastorek; Andrea Scozzafava; Silvia Pastoreková; Claudiu T. Supuran
- Book ID
- 108073541
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 143 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0960-894X
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