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Molecular Cloning, Characterization, and Inhibition Studies of the Rv1284 β-Carbonic Anhydrase from Mycobacterium tuberculosis with Sulfonamides and a Sulfamate

✍ Scribed by Minakuchi, Tomoko; Nishimori, Isao; Vullo, Daniela; Scozzafava, Andrea; Supuran, Claudiu T.


Book ID
120164430
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
836 KB
Volume
52
Category
Article
ISSN
0022-2623

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✍ Anthony Bertucci; Alessio Innocenti; Andrea Scozzafava; Sylvie Tambutté; Didier 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 211 KB

The catalytic activity and the inhibition of a new coral carbonic anhydrase (CA, EC 4.2.1.1), from the scleractinian coral Stylophora pistillata, STPCA-2, has been investigated. STPCA-2 has high catalytic activity for the physiological reaction being less sensitive to anion and sulfonamide inhibitor