Carbon-13 nuclear magnetic resonance studies of some 9-alkoxy- and 9-alkylthio-acridines
โ Scribed by R. Faure; J.-P. Galy; A. Mahamoud; E.-J. Vincent; A.-M. Galy; J. Barbe
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 184 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0749-1581
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## Abstract ^13^C NMR chemical shifts of six pyrazolo[__a__]โ9(10__H__)โacridinones are reported; they were assigned on the basis of multiplicities, carbonโproton coupling constants, selective proton decoupling experiments and comparison with related substances.
13C NMR data are presented for 31 variously substituted derivatives of 9acridanone and 15 derivatives of 9-thioacridanone. Unexpected shifts are explained in terms of hydrogen bonding or tautomeric equilibria.
REFERENCE DATA causes the electron density to be comparatively lower at C-3 and C-5 than at C-2 and C-4, so that the former signals resonate at lower fields. Distinction between the signals of the C-2/C-4 and C-3/C-5 pairs was achieved by comparing the C-H coupling patterns of 5 and 1. Compounds 1,
## Abstract Fourier transform carbonโ13 nuclear magnetic resonance spectra have been obtained and interpreted for some 2โsubstituted tetrahydropyrans. The effects of the substituents on ฮฑ, ฮฒ, ฮณ and ฮดโcarbon atoms are discussed. Using suitable reference compounds the ฮณโparameter can be used for quan