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Carbocyclic galanthamin analogs: 4a,5,9,10,11,12-hexahydro-6H-benzo[b]cyclohepta[cd]benzofurans

✍ Scribed by Matthias Treu; Christian Hametner; Johannes Frohlich; Ulrich Jordis; Kurt Mereiter

Book ID: 102339943
Publisher: Journal of Heterocyclic Chemistry
Year: 2002
Tongue: English
Weight: 78 KB
Volume: 39
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570390626

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✦ Synopsis

Abstract

The synthesis of a novel unnatural carbocyclic analog of the acetylcholine esterase inhibitor galanthamine with a K~3~[Fe(CN)~6~] promoted oxidative tandem cyclization as the key step is reported.

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