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8-(4-Chlorophenyl)-11,11-dimethyl-5,9-dioxo-6,8,9,10,11,12-hexahydro-5H-quinolino[1,2-a]quinazoline-7-carbonitrile N,N-dimethylformamide solvate

✍ Scribed by Jiang, Hong ;Wu, Shanshan ;Li, Chunmei

Publisher: International Union of Crystallography
Year: 2007
Tongue: English
Weight: 621 KB
Volume: 63
Category: Article
ISSN: 1600-5368
DOI: 10.1107/s1600536807054037

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✦ Synopsis

The title compound, C 25 H 20 ClN 3 O 2 ÁC 3 H 7 NO, was synthesized by the reaction of 4-chlorobenzaldehyde, 2-(5,5-dimethyl-3oxocyclohex-1-enylamino)benzoic acid and malononitrile in ethylene glycol under microwave irradiation. The dihydropyridine and pyrimidine rings both adopt boat conformations. The cyclohexene ring adopts an envelope conformation. In the crystal structure, the main molecules exist as N-HÁ Á ÁO hydrogen-bonded dimers. The crystal packing is further stabilized by C-HÁ Á ÁO and C-HÁ Á Á interactions. The N,N-dimethylformamide molecules lie within a channel formed by the quinolino[1,2-a]quinazoline molecules.

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