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Capillary GC-MS investigation of the metabolism and excretion of oxabolone in man

✍ Scribed by Barbarulo, Maria Vittoria ;Buiarelli, Francesca ;Ciardi, Massino ;Giarrusso, Alberto ;Rosati, Felice ;Cartoni, G. P.

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 380 KB
Volume: 18
Category: Article
ISSN: 0935-6304
DOI: 10.1002/jhrc.1240181106

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✦ Synopsis

Abstract

The metabolism of oxabolone cipionate, 17‐(3‐cyclopentyl‐1‐oxopropoxy)‐4‐hydroxyestr‐4‐en‐3‐one, a synthetic anabolic steroid, was investigated in man, the cumulative urinary excretion and the metabolism of the compounds being studied by GC‐MS in both electron impact and chemical ionization modes. After administration by injection to volunteers, five different metabolities were detected in urine. The metabolites and the parent compound were detected in urine up to a week after administration.

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