## Abstract A new method for the CE separation of nine tricyclic antidepressants (TCAs), __viz__. amitriptyline, clomipramine, desipramine, doxepin, fluphenazine, imipramine, nortriptyline, promazine, and thioridazine, is described. The capillary was statically coated with a layer of poly(__N__,__N
Capillary electrophoretic separation of tricyclic antidepressants using charged carboxymethyl-β-cyclodextrin as a buffer additive
✍ Scribed by Brian J. Spencer; Wenbin Zhang; Professor William C. Purdy
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 607 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0173-0835
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## Abstract High resolution could be achieved for the enantiomers of acidic drugs, namely, sulindac, fenoprofen, ketoprofen, warfarin, and hexobarbital, in a buffer of pH 3 by the simultaneous addition of uncharged and charged β‐cyclodextrin derivatives. The interaction of the analytes with the ani
The feasibility of enantiomer separation by capillary electrochromatog-Ž . Ž . raphy CEC was shown on 75-m i.d. capillary columns packed with 3-m bare w Ž . silica packings. Racemic phenylephrine 3-hydroxy-␣methylaminomethyl benzyl x w Ž . x alconhol and synephrine 4-hydroxy-␣-methylaminomethyl ben