## Abstract Multiβcomponent mixtures of controlled drugs, drug impurities, and adulterants have been analyzed by capillary SFCβFID, packed column SFCβUV, and capillary SFCβMS. Isocratic packed column SFC has been performed with binary and ternary mobile phases using a single syringe pump. The combi
Capillary and packed column SFC/MS
β Scribed by Berry, A. J. ;Games, D. E. ;Mylchreest, I. C. ;Perkins, J. R. ;Pleasance, S.
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 394 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0935-6304
No coin nor oath required. For personal study only.
β¦ Synopsis
A frit restrictor interface for capillary column supercritical fluid chromatography/mass spectrometry (SFC/MS) has been constructed and used for the analysis of high boiling point alkanes. Packed column SFC/MS is described using both a moving belt liquid chromatographic/mass spectrometric interface and a thermospray source in the filament-on mode.
π SIMILAR VOLUMES
## Abstract Several commercially available and homeβmade reversed phase packing materials packed in capillary columns are evaluated for SFC with pure CO~2~ as mobile phase. Anilines and polycyclic aromatic hydrocarbons are used as test mixture. Some βon column endcappingβ experiments are evaluated.
## Abstract Preparation of packed capillary columns with supercritical carbon dioxide as the packing carrier is demonstrated; column performance was evaluated by both HPLC and SFC. It is shown that this procedure yields excellent column performance. The density of the packed bed can be controlled b
## Abstract Residual adsorptive activity of reversed phase (RP) column packings used in supercritical fluid chromatography (SFC) can be significantly reduced by a dynamic __inβsitu__ silanization with diphenyltetramethyldisilazane (DPTMDS). RPβmaterials thus deactivated were characterized both chro
## Abstract The packed capillary column is one type of microcolumn. It is used increasingly in liquid chromatography, supercritical fluid chromatography, and multidimensional chromatography. In order to attain high efficiency with packed capillary columns, reliable column preparation methods must b