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Canonical and non-canonical Wnts affect osteogenic differentiation of primary human adipose tissue-derived mesenchymal stem cells

✍ Scribed by A. Santos⁎; A.D. Bakker; J.M.A. de Blieck-Hogervorst; J. Klein-Nulend

Book ID
116321965
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
90 KB
Volume
44
Category
Article
ISSN
8756-3282

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## Abstract This study examines the role of Wnt signaling events in regulating the differential potential of mesenchymal stem cells (MSCs) from adult bone marrow (BM). Immunohistochemical analysis of BM revealed co‐localization of Wnt5a protein, a non‐canonical Wnt, with CD45^+^ cells and CD45^−^ S