Osteogenic differentiation and osteochondral tissue engineering using human adipose-derived stem cells
โ Scribed by Mahmoudifar, Nastaran; Doran, Pauline M.
- Book ID
- 118273645
- Publisher
- American Institute of Chemical Engineers
- Year
- 2012
- Tongue
- English
- Weight
- 836 KB
- Volume
- 29
- Category
- Article
- ISSN
- 8756-7938
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## Abstract Human adiposeโderived stem cells (hADSC) are capable of differentiating into an osteogenic lineage. It is believed that microRNAs (miRNAs) play important roles in regulating this osteogenic differentiation of human adiposeโderived cells, although its molecular mechanism remains unclear.
## Abstract ## Objectives/Hypothesis: One potential treatment option for severe vocal fold scarring is to replace the vocal fold cover layer with a tissueโengineered structure containing autologous cells. As a first step toward that goal, we sought to develop a threeโdimensional cellโpopulated mat