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Canonical Wnt3A activates non-canonical Wnt/JNK signaling pathway and determines differentiation fate of human skeletal (mesenchymal) stem cell

โœ Scribed by W. Qiu; M. Kassem


Book ID
116324365
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
57 KB
Volume
48
Category
Article
ISSN
8756-3282

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## Abstract This study examines the role of Wnt signaling events in regulating the differential potential of mesenchymal stem cells (MSCs) from adult bone marrow (BM). Immunohistochemical analysis of BM revealed coโ€localization of Wnt5a protein, a nonโ€canonical Wnt, with CD45^+^ cells and CD45^โˆ’^ S