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Cancer chemopreventive and anti-angiogenic activities of xanthohumol from hop (Humulus lupulus L.)

✍ Scribed by C. Gerhauser; R. Hussong; E. Bertl; K. Klimo; N. Frank; H. Bartsch; H. Becker

Book ID
118624819
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
130 KB
Volume
4
Category
Article
ISSN
1359-6349

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Broad spectrum antiinfective potential o
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This review summarizes the capacity of xanthohumol (XN) in comparison with additional hop constituents and metabolites to act as an antiinfective agent against microorganisms including bacteria, viruses, fungi and malarial protozoa. XN was shown to inhibit the Gram-positive bacteria Staphylococcus a

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## Abstract The female flowers of hops (__Humulus lupulus__ L.) used to flavor beer contain the prenylated flavonoids xanthohumol (XN) and isoxanthohumol (IX). IX is moderately estrogenic __in vitro__ and XN has pharmacological properties that might make it useful as a cancer chemopreventive agent.

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Antiinvasive effect of xanthohumol, a prenylated chalcone present in hops (Humulus lupulus L.) and beer
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## Abstract The female inflorescences of the hop plant (__Humulus lupulus__ L.) are essential during brewing to add taste and flavor to beer and to stabilize beer foam. Xanthohumol, the main prenylated chalcone in hops, was investigated for its antiinvasive activity on human breast cancer cell line