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CANCER AND CARDIAC DEATHS IN OBLIGATORY ATAXIA-TELANGIECTASIA HETEROZYGOTES

✍ Scribed by Swift, Michael; Chase, Charles

Book ID
123523401
Publisher
The Lancet
Year
1983
Tongue
English
Weight
360 KB
Volume
321
Category
Article
ISSN
0140-6736

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✍ BΓ©atrice Geoffroy-Perez; Nicolas Janin; Katia Ossian; Anthony LaugΓ©; Marie-FranΓ§ πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 60 KB

Epidemiological studies have suggested that ataxia-telangiectasia (AT) heterozygotes have a predisposition to cancer, especially breast cancer in women. Now, haplotyping can identify heterozygotes for AT mutation (ATM) in AT families, allowing the risk of cancer associated with ATM heterozygosity st