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Breast cancer and radiotherapy in ataxia-telangiectasia heterozygote

✍ Scribed by J. Ramsay; G. Birrell; M. Lavin


Book ID
118561577
Publisher
The Lancet
Year
1996
Tongue
English
Weight
231 KB
Volume
347
Category
Article
ISSN
0140-6736

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Epidemiological studies have suggested that ataxia-telangiectasia (AT) heterozygotes have a predisposition to cancer, especially breast cancer in women. Now, haplotyping can identify heterozygotes for AT mutation (ATM) in AT families, allowing the risk of cancer associated with ATM heterozygosity st