Can Insulin Therapy Delay or Prevent Insulin-Dependent Diabetes Mellitus?
โ Scribed by Reena Kakka; Mary Anne Koda-Kimble
- Book ID
- 112113619
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 697 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0277-0008
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Recent advances in the understanding of the pathogenesis of insulin-dependent diabetes mellitus (IDDM) have led to the first trials of disease prevention in susceptible individuals. Two main trials (nicotinamide and insulin) are now running but first results will not be available before the turn of
A controlled trial of oral nicotinamide to prevent the onset of diabetes mellitus in high risk children was conducted in two centres. The selection criteria were age less than 16 years, islet cell antibody > 80 IUs, and first phase insulin release < 5th percentile. All of eight untreated control sub