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✦   LIBER   ✦

Prevention of insulin-dependent diabetes mellitus 1998

✍ Scribed by Pozzilli, Paolo

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
100 KB
Volume
14
Category
Article
ISSN
0742-4221

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✦ Synopsis

Recent advances in the understanding of the pathogenesis of insulin-dependent diabetes mellitus (IDDM) have led to the first trials of disease prevention in susceptible individuals. Two main trials (nicotinamide and insulin) are now running but first results will not be available before the turn of the century. Pilot trials using different approaches, most of them based on the induction of immunotolerance, are also under way and should offer new insight for establishing larger multicentre studies including attempts aimed at primary prevention by removal of diabetogenic components in cow's milk. The field is moving fast and it is expected that intervention for IDDM prevention will be offered to an increasing number of individuals found at risk of developing the disease.

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