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Can human ICAM-1 transgenic mice be used for the study of human cerebral malaria pathogenesis?

✍ Scribed by M Ito; Y Matsumoto; M Aikawa


Book ID
119604529
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
163 KB
Volume
47
Category
Article
ISSN
1383-5769

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Sera from transgenic mice (TM) carrying human genes of alpha 1-acid glycoprotein (orosomucoid or ORM) have been analyzed by isoelectrofocusing and subsequent immunoblotting with antihuman ORM antibodies. With this technique it is possible to reveal selectively the human protein secreted in the TM se