In mass spectrometry, the ions of interest are usually detected by techniques based on secondary electron emission using electron multipliers or micro-channel plates. For large ions of biological interest, these detection techniques are inefficient and eventually break down as the ion mass increases
Calorimetric Detectors for High Mass Ions
β Scribed by Norman E. Booth
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 235 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0951-4198
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β¦ Synopsis
In mass spectrometry, the ions of interest are usually detected by techniques based on secondary electron emission using electron multipliers or micro-channel plates. For large ions of biological interest, these detection techniques are inefficient and eventually break down as the ion mass increases. We discuss the use of low-temperature detectors which have an efficient response which extends to the highest masses. Recent tests show that a low-temperature calorimetric detector can measure the kinetic energy of individual incident ions irrespective of their mass or charge state. This detection scheme, when used in a time-of-flight spectrometer, could yield both the mass and the charge state of individual ions.
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