𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Energy-sensitive cryogenic detectors for high-mass biomolecule mass spectrometry

✍ Scribed by Matthias Frank; Simon E. Labov; Garrett Westmacott; W. Henry Benner

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
483 KB
Volume
18
Category
Article
ISSN
0277-7037

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✦ Synopsis

detectors can be used for charge discrimination and studies of ion fragmentation, ion-detector interaction, and internal energies of large molecular ions. Cryogenic detectors could therefore prove to be a valuable diagnostic tool in TOF±MS.

Here, we give a general introduction to the cryogenic detector types most applicable to TOF±MS including those types already used in several TOF±MS experiments. We review and compare the results of these experiments, discuss practical aspects of operating cryogenic detectors in TOF±MS systems, and describe potential near future improvements of cryogenic detectors for applications in mass spectrometry.

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