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Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD

✍ Scribed by B.B. Friday; P.O. Mitchell; K.M. Kegley; G.K. Pavlath


Book ID
114428830
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
549 KB
Volume
71
Category
Article
ISSN
0301-4681

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## Abstract Calcium is a key element in intracellular signaling in skeletal muscle. Changes in intracellular calcium levels are thought to mediate the fast‐to‐slow transformation of muscle fiber type. One factor implicated in gene regulation in adult muscle is the nuclear factor of activated T‐cell