MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation

Hepatocyte growth factor (HGF) inhibits

Hepatocyte growth factor (HGF) inhibits skeletal muscle cell differentiation: A role for the bHLH protein twist and the cdk inhibitor p27

✍ Yael Leshem; Douglas B. Spicer; Ronit Gal-Levi; Orna Halevy 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 281 KB 👁 1 views

Hepatocyte growth factor (HGF) plays a crucial role in regulating the differentiation of both fetal and adult skeletal myoblasts. This study aimed at defining the intracellular factors that mediate the effect of HGF on adult myoblast differentiation. HGF increased Twist expression while decreasing p