c-Jun enhancement of androgen receptor transactivation is associated with prostate cancer cell proliferation
β Scribed by Chen, S-Y; Cai, C; Fisher, C J; Zheng, Z; Omwancha, J; Hsieh, C-L; Shemshedini, L
- Book ID
- 110070722
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 503 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0950-9232
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## Abstract To elucidate the mechanism of androgenβdependent cellular proliferation in prostate cancer, androgenβdependent alterations of individual cell cycle regulatory proteins in the androgenβsensitive prostate cancer cell line LNCaP were evaluated. LNCaP cells were deprived of androgens by cul
## Abstract We previously demonstrated that ectopic expression of neurotrophic peptide (NP) derived from saposin C promotes androgen receptor (AR) expression and transactivation in human prostate cancer cells. This prompted us to investigate how NP or saposin C can function in cells. We constructed