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Stearoyl CoA desaturase (SCD) facilitates proliferation of prostate cancer cells through enhancement of androgen receptor transactivation

✍ Scribed by Seung-Jin Kim; Hojung Choi; Sung-Soo Park; Chawnshang Chang; Eungseok Kim

Book ID: 106263179
Publisher: Korean Society for Molecular and Cellular Biology
Year: 2011
Tongue: English
Weight: 492 KB
Volume: 31
Category: Article
ISSN: 1016-8478
DOI: 10.1007/s10059-011-0043-5

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## Abstract Androgen and androgen receptor (AR) are involved in growth of normal prostate and development of prostatic diseases including prostate cancer. Androgen deprivation therapy is used for treating advanced prostate cancer. This therapeutic approach focuses on suppressing the accumulation of