✦ LIBER ✦

C-7 functionalization of 6,7-dihydro[5H]pyrrolo[1,2-a]imidazoles: Activation via quaternization with MEMCl

✍ Scribed by Timothy F. Gallagher; Jerry L. Adams

Book ID: 104212286
Publisher: Elsevier Science
Year: 1989
Tongue: French
Weight: 286 KB
Volume: 30
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)70628-9

No coin nor oath required. For personal study only.

✦ Synopsis

Several 6,

pyrrolo[1,2-a]imidazoles were activated toward functionalization at C-7 by conversion to quaternary imidazolium salts. The MEMCl derived quaternary salts upon treatment with base reacted with both aldehydes and alkyl halides. The MEM group was removed under mild conditions by heating the functional&d adducts in a variety of solvents.

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