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Buccal and oral bioavailability of naloxone and naltrexone in rats

โœ Scribed by Hussain, Munir A.; Aungst, Bruce J.; Kearney, Albert; Shefter, Eli


Book ID
120763377
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
346 KB
Volume
36
Category
Article
ISSN
0378-5173

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โœ Harlan E. Shannon; Stephen G. Holtzman ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› Springer ๐ŸŒ English โš– 589 KB

The capacity of the specific narcotic antagonists naltrexone and naloxone to block the discriminative effects produced by morphine in the rat were evaluated using a two-choice, discrete-trial avoidance task. The antagonists produced a dose-dependent and time-dependent blockade of morphine's effects