✦ LIBER ✦

BS2-1 Sterol regulatory element-binding protein-1c activation is implicated in pancreatic β-cell lipotoxicity

✍ Scribed by Hao-ming Tian; Jian-wei Li; Jing-qiu Cheng; Xiao-jing Liu

Book ID: 117370900
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 70 KB
Volume: 79
Category: Article
ISSN: 0168-8227
DOI: 10.1016/s0168-8227(08)70681-8

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Sterol regulatory element–binding protei

Sterol regulatory element–binding protein-1c and pancreatic β-cell dysfunction

✍ H. Shimano; M. Amemiya-Kudo; A. Takahashi; T. Kato; M. Ishikawa; N. Yamada 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 236 KB

High density lipoprotein inhibits the ac

High density lipoprotein inhibits the activation of sterol regulatory element-binding protein-1 in cultured cells

✍ Masaki Yoshida; Nagakatsu Harada; Keiko Yoshida; Tadahiko Nakagawa; Takaaki Shim 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 942 KB

Aberrant activation of liver X receptors

Aberrant activation of liver X receptors impairs pancreatic beta cell function through upregulation of sterol regulatory element-binding protein 1c in mouse islets and rodent cell lines

✍ Z. X. Meng; Y. Yin; J. H. Lv; M. Sha; Y. Lin; L. Gao; Y. X. Zhu; Y. J. Sun; X. H 📂 Article 📅 2012 🏛 Springer 🌐 English ⚖ 495 KB

AMP-activated protein kinase suppresses

AMP-activated protein kinase suppresses LXR-dependent sterol regulatory element-binding protein-1c transcription in rat hepatoma McA-RH7777 cells

✍ Jian Yang; Lauren Craddock; Sharon Hong; Zhi-Mei Liu 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 474 KB

## Abstract AMP‐activated protein kinase (AMPK) is an intracellular fuel sensor that plays a key role in regulating fatty acid synthesis in liver. Sterol regulatory element‐binding protein (SREBP)‐1c is a master regulator of hepatic lipogenic gene expression. It has long been documented that AMPK a

A rare missense mutation in a type 2 dia

A rare missense mutation in a type 2 diabetes patient decreases the transcriptional activity of human sterol regulatory element binding protein-1

✍ Santiago Vernia; Delphine Eberlé; Antonio Hernandez Mijares; Fabienne Foufelle; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 196 KB

Sterol regulatory element binding protein 1 (SREBP-1) transcription factors play a key role in energy homeostasis by regulating genes involved in both carbohydrate and lipid metabolism, and in adipocyte differentiation. The 5' end of the mRNA-encoding SREBP-1 exists in two forms, designated 1a and 1

Phosphorylation of cyclic AMP-response e

Phosphorylation of cyclic AMP-response element–binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1)

✍ Ivonne Bazwinsky-Wutschke; Sabine Wolgast; Eckhard Mühlbauer; Elke Albrecht; Elm 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 653 KB