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Sterol regulatory element–binding protein-1c and pancreatic β-cell dysfunction

✍ Scribed by H. Shimano; M. Amemiya-Kudo; A. Takahashi; T. Kato; M. Ishikawa; N. Yamada


Book ID
109044554
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
236 KB
Volume
9
Category
Article
ISSN
1462-8902

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## Abstract AMP‐activated protein kinase (AMPK) is an intracellular fuel sensor that plays a key role in regulating fatty acid synthesis in liver. Sterol regulatory element‐binding protein (SREBP)‐1c is a master regulator of hepatic lipogenic gene expression. It has long been documented that AMPK a