The model of angiotensin II (ANG II) developed in our laboratory using a combination of NMR, fluorescence data and molecular graphics [Matsoukas, J.M. et al., J. Biol. Chem., 269 (1994) 5303] served as a template for a systematic superimposition of potent AT~ receptor antagonists with ANG II. The ke
Bromobenzofurans : a new class of potent, non-peptide antagonists of angiotensin II
β Scribed by D Middlemiss; G.M. Drew; B.C. Ross; M.J. Robertson; D.I.C. Scopes; M.D. Dowle; J Akers; K Cardwell; K.L. Clark; S Coote; C.D. Eldred; J Hamblett; A Hilditch; G.C. Hirst; T Jack; J Montana; T.A. Panchal; J.M.S. Paton; P Shah; G Stuart; A Travers
- Book ID
- 108477086
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 370 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0960-894X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
## Abstract magnified image Several novel analogues of Losartan **2** were synthesized as potential nonβpeptide angiotensin (**II**) receptor antagonists. In these nonβpeptide analogues, the tetrazole and the substituted imidazole rings of Losartan **2** were replaced, respectively, by a carboxyli