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Bridged cyclams as imaging agents for chemokine receptor 4 (CXCR4)

✍ Scribed by Woodard, Lauren E.; De Silva, Ravindra A.; Behnam Azad, Babak; Lisok, Ala; Pullambhatla, Mrudula; G. Lesniak, Wojciech; Mease, Ronnie C.; Pomper, Martin G.; Nimmagadda, Sridhar

Book ID
122178400
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
954 KB
Volume
41
Category
Article
ISSN
0969-8051

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## Abstract The chemokine receptor CXCR4 possesses multiple critical functions in normal and pathologic physiology. CXCR4 is a G‐protein‐coupled receptor that transduces signals of its endogenous ligand, the chemokine CXCL12 (stromal cell‐derived factor‐1, SDF‐1). The interaction between CXCL12 and