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ChemInform Abstract: Imaging Agents for the Chemokine Receptor 4 (CXCR4)

✍ Scribed by Joeri Kuil; Tessa Buckle; Fijs W. B. van Leeuwen

Book ID
115553726
Publisher
John Wiley and Sons
Year
2012
Weight
18 KB
Volume
43
Category
Article
ISSN
0931-7597

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## Abstract The chemokine receptor CXCR4 possesses multiple critical functions in normal and pathologic physiology. CXCR4 is a G‐protein‐coupled receptor that transduces signals of its endogenous ligand, the chemokine CXCL12 (stromal cell‐derived factor‐1, SDF‐1). The interaction between CXCL12 and