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BRCA1 Required for Transcription-Coupled Repair of Oxidative DNA Damage

โœ Scribed by Gowen, L. C.


Book ID
121159850
Publisher
American Association for the Advancement of Science
Year
1998
Tongue
English
Weight
684 KB
Volume
281
Category
Article
ISSN
0036-8075

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Emerging roles of BRCA1 in transcription
โœ Yumay Chen; Wen-Hwa Lee; Helen K. Chew ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 206 KB ๐Ÿ‘ 2 views

BRCA1 was the first breast cancer susceptibility gene to be identified and cloned. In individuals from high-risk families, mutations in BRCA1 increase the lifetime risk of developing breast cancer eight to tenfold, compared to the general population. How the BRCA1 protein product normally functions