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BRCA1 promoter methylation in peripheral blood cells is associated with increased risk of breast cancer with BRCA1 promoter methylation

✍ Scribed by Takashi Iwamoto; Noriaki Yamamoto; Tetsuya Taguchi; Yasuhiro Tamaki; Shinzaburo Noguchi


Publisher
Springer US
Year
2010
Tongue
English
Weight
889 KB
Volume
129
Category
Article
ISSN
0167-6806

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Inherited susceptibility to breast cancer results from germline mutations in one of a number of genes including BRCA1. A significant number of BRCA1-linked familial breast cancer patients, however, have no detectable BRCA1 mutation. This could be due in part to the inability of commonly used mutatio