Single-nucleotide polymorphisms in the p
β
Ronit I. Yarden; Eitan Friedman; Sally Metsuyanim; Tzvia Olender; Edna Ben-Asher
π
Article
π
2010
π
John Wiley and Sons
π
English
β 367 KB
## Abstract Germline mutations in the BRCA1 and BRCA2 genes are associated with a significantly increased lifetime risk for developing breast and/or ovarian cancer. However, incomplete penetrance and substantial variability in age of disease onset among carriers of the same mutation suggests the in