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BRAF mutation common to 70% of thyroid carcinomas

✍ Scribed by Khabir Ahmad

Book ID: 117782904
Publisher: The Lancet
Year: 2003
Tongue: English
Weight: 90 KB
Volume: 4
Category: Article
ISSN: 1470-2045
DOI: 10.1016/s1470-2045(03)01127-6

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## Abstract ## Background. An activating point mutation of the __BRAF__ oncogene results in a V600E amino acid missense mutation found in a majority of papillary thyroid carcinomas (PTC). ## Methods. In this study, 28 matched tumor and serum samples obtained from patients with both benign and ma