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RET rearrangements and BRAF mutation in undifferentiated thyroid carcinomas having papillary carcinoma components

✍ Scribed by Kunio Mochizuki; Tetsuo Kondo; Tadao Nakazawa; Masanori Iwashina; Tomonori Kawasaki; Nobuki Nakamura; Tetsu Yamane; Shin-ichi Murata; Koichi Ito; Kaori Kameyama; Makio Kobayashi; Ryohei Katoh


Book ID
110092793
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
426 KB
Volume
57
Category
Article
ISSN
0309-0167

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## Abstract ## Background. An activating point mutation of the __BRAF__ oncogene results in a V600E amino acid missense mutation found in a majority of papillary thyroid carcinomas (PTC). ## Methods. In this study, 28 matched tumor and serum samples obtained from patients with both benign and ma