## Abstract Gene mutations in __APC__, __Kβras__, and __p53__ are thought to be essential events for colorectal cancer development. Recent data seem to indicate that __Kβras__ and __p53__ mutations rarely coβexist in the same tumor, indicating that these alterations do not represent a synergistic e
β¦ LIBER β¦
BRAF and K-ras gene mutations in human pancreatic cancers
β Scribed by Norihisa Ishimura; Kunihiro Yamasawa; Mohammad Azharul Karim Rumi; Yasunori Kadowaki; Shunji Ishihara; Yuji Amano; Yoshinori Nio; Tetsuya Higami; Yoshikazu Kinoshita
- Book ID
- 117467903
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 124 KB
- Volume
- 199
- Category
- Article
- ISSN
- 0304-3835
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Mutations in codon I 2 of K-ras occur in a high proportion of pancreatic cancer cases. Although there is evidence that p53 mutations also occur in this tumor, few studies have been reported to date and no comparison has been made of K-ras and p53 mutations in the same tissues. Single-strand conforma