𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Prevalence of ras gene mutations in human colorectal cancers

✍ Scribed by Bos, Johannes L.; Fearon, Eric R.; Hamilton, Stanley R.; Vries, Matty Verlaan–de; van Boom, Jacques H.; van der Eb, Alex J.; Vogelstein, Bert


Book ID
109749544
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
666 KB
Volume
327
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Mutations of the PIK3CA gene in heredita
✍ Michiko Miyaki; Takeru Iijima; Tatsuro Yamaguchi; Keiichi Takahashi; Hiroshi Mat 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 110 KB 👁 1 views

## Abstract Somatic mutations of the __PIK3CA__ gene have recently been detected in various human cancers, including sporadic colorectal cancer. However, mutations of the __PIK3CA__ gene in hereditary colorectal cancers have not been clarified. To elucidate the mutation status in familial adenomato

K-ras and p53 mutations in hereditary no
✍ Lorena Losi; Maurizio Ponz de Leon; Josef Jiricny; Carmela Di Gregorio; Piero Be 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 57 KB 👁 2 views

Genetic instability related to defective DNA mismatch repair genes may be involved in the pathogenesis of carcinoma in Hereditary Non-Polyposis Colorectal Cancer (HN-PCC). To test that the targets of genetic instability could include critical transforming genes involved in colon tumor progression, w

Ras gene mutation and amplification in h
✍ William E. Pierceall; Leonard H. Goldberg; Michael A. Tainsky; Tapas Mukhopadhya 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 719 KB

Our previous studies have shown that human skin cancers occurring on sun-exposed body sites frequently contain activated Ha-ras oncogenes capable of inducing morphologic and tumorigenic transformation of NIH 3T3 cells. In this study, we analyzed human primary squamous cell carcinomas (SCCs) and basa

Prevalence of G-TO-T transversions among
✍ Nadežda Urošević; Aleksandar Dujić; Koviljka Krtolica; Andjelija Škaro-Milić; Sl 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 961 KB

Human colorectal carcinoma tissue sampled from 37 patients, routinely graded into Dukes' stages A, B and C and histologically examined for the level of differentiation, were analyzed for the presence of point mutations in the K-ros oncogene. Seventeen cases out of the 37 analyzed were found to have