✦ LIBER ✦

Mutations of the BRAF gene in human cancer

✍ Scribed by Davies, Helen; Bignell, Graham R.; Cox, Charles; Stephens, Philip; Edkins, Sarah; Clegg, Sheila; Teague, Jon; Woffendin, Hayley; Garnett, Mathew J.; Bottomley, William

Book ID: 109890266
Publisher: Nature Publishing Group
Year: 2002
Tongue: English
Weight: 349 KB
Volume: 417
Category: Article
ISSN: 0028-0836
DOI: 10.1038/nature00766

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

BRAF and KRAS mutations in stomach cance

BRAF and KRAS mutations in stomach cancer

✍ Lee, Sug Hyung; Lee, Jong Woo; Soung, Young Hwa; Kim, Hong Sug; Park, Won Sang; 📂 Article 📅 2003 🏛 Nature Publishing Group 🌐 English ⚖ 141 KB

Mutations of the BRAF gene in ulcerative

Mutations of the BRAF gene in ulcerative colitis-related colorectal carcinoma

✍ Daniela E. Aust; Michael Haase; Lyudmyla Dobryden; Annett Markwarth; Udo Löhrs; 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 263 KB 👁 1 views

## Abstract The __Raf/MEK/ERK (MAPK)__ signal transduction cascade is an important mediator of a number of cellular fates including growth, proliferation and survival. The __BRAF__ gene is activated by oncogenic __Ras__, leading to cooperative effects in cells responding to growth factor signals. O

BRAF mutations in an Italian cohort of t

BRAF mutations in an Italian cohort of thyroid cancers

✍ Laura Fugazzola; Deborah Mannavola; Valentina Cirello; Guia Vannucchi; Marina Mu 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 85 KB

TRAIL receptor upregulation and the impl

TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors

✍ Eftychia Oikonomou; Vivian Kosmidou; Anastasia Katseli; Konstantinos Kothonidis; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 273 KB 👁 2 views

## Abstract TRAIL raises hopes as a promising anti‐tumor agent due to its selectivity toward cancer cells. Higher expression of its pro‐death receptors TRAIL‐R1 (DR4) and TRAIL‐R2 (DR5) attenuates higher sensitivity to TRAIL‐induced apoptosis, and represents a marker for better cancer prognosis and

Mutational analysis of the ARAF gene in

Mutational analysis of the ARAF gene in human cancers

✍ JONG WOO LEE; YOUNG HWA SOUNG; SU YOUNG KIM; WON SANG PARK; SUK WOO NAM; WOO SUN 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 93 KB

Mutation analysis of p53, K-ras, and BRA

Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression

✍ Daniele Calistri; Claudia Rengucci; Ian Seymour; Arturo Lattuneddu; Anna maria P 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 162 KB

## Abstract Gene mutations in __APC__, __K‐ras__, and __p53__ are thought to be essential events for colorectal cancer development. Recent data seem to indicate that __K‐ras__ and __p53__ mutations rarely co‐exist in the same tumor, indicating that these alterations do not represent a synergistic e