## Abstract ## BACKGROUND. The prognosis of patients with chronic myelogenous leukemia (CML) after failure of imatinib mesylate therapy is not well documented. ## METHODS. The outcome of 420 patients with CML postβimatinib failure (resistanceβrecurrence in 374; toxicities in 46) were reviewed in
Bosutinib: A Review of Its Use in Patients with Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia
β Scribed by Syed, Yahiya Y.; McCormack, Paul L.; Plosker, Greg L.
- Book ID
- 121566348
- Publisher
- Springer International Publishing AG
- Year
- 2014
- Tongue
- English
- Weight
- 408 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1173-8804
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Background: Patients with chronic myelogenous leukemia (cml) occasionally experience persistent thrombocythemia despite having adequate white blood cell (wbc) counts. trimethylenethiophosphoramide (thiotepa) is an alkylating agent that significantly inhibits platelet production. ## Methods: Th
## Abstract ## BACKGROUND Anecdotal cases of chromosomal abnormalities in Philadelphia chromosome (Ph)βnegative metaphases have been reported in patients with chronic myelogenous leukemia (CML) in the chronic phase during treatment with interferon and, more recently, with imatinib. This phenomenon