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A pilot study of all-trans retinoic acid in patients with Philadelphia chromosome-positive chronic myelogenous leukemia

✍ Scribed by Cortes, J; Kantarjian, H; O’Brien, S; Beran, M; Estey, E; Keating, M; Talpaz, M

Book ID
110053532
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
218 KB
Volume
11
Category
Article
ISSN
0887-6924

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✍ Edgardo J. Rodriguez-Monge; Jorge E. Cortes; Susan O'Brien; Moshe Talpaz; Hagop 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 102 KB 👁 3 views

## Background: Patients with chronic myelogenous leukemia (cml) occasionally experience persistent thrombocythemia despite having adequate white blood cell (wbc) counts. trimethylenethiophosphoramide (thiotepa) is an alkylating agent that significantly inhibits platelet production. ## Methods: Th