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Bone Morphogenetic Protein-7 (OP1) and Transforming Growth Factor-β1 Modulate 1,25(OH)2-Vitamin D3-Induced Differentiation of Human Osteoblasts

✍ Scribed by Annegret Eichner; Josef Brock; Carl-Henrik Heldin; Serhiy Souchelnytskyi


Book ID
115604247
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
779 KB
Volume
275
Category
Article
ISSN
0014-4827

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The process of recombinant human bone morphogenetic protein-2 (rhBMP-2)induced endochondral ossification involves 1 ) the proliferation and differentiation of mesenchymal cells into chondroblasts and osteoblasts; 2) the production and maturation of cartilage and bone matrix; and 3 ) the differentiat