Opposite effects of bone morphogenetic protein-2 and transforming growth factor-β1 on osteoblast differentiation
✍ Scribed by S Spinella-Jaegle; S Roman-Roman; C Faucheu; F.-W Dunn; S Kawai; S Galléa; V Stiot; A.M Blanchet; B Courtois; R Baron; G Rawadi
- Book ID
- 117807464
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 263 KB
- Volume
- 29
- Category
- Article
- ISSN
- 8756-3282
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Transforming growth factor+ (TGF-P) and bone morphogenetic protein 4 (BMP 4) are both able, under certain circumstances, to induce endochondral bone forrnation in vivo. This study compared the effects of TGF-Pl and BMP 4 on the gene expression of a retinoic acid (RA) responsive rat clonal preosteobl
Osteoprogenitor cells in the human bone marrow stroma can be induced to differentiate into osteoblasts under stimulation with hormonal and local factors. We previously showed that human bone marrow stromal (HBMS) cells respond to dexamethasone and vitamin D by expressing several osteoblastic markers
Systemic and local factors regulate the activity of osteoblasts and osteoclasts during bone growth and remodeling by modulating a complex array of intracellular signaling events. Recent genetic evidence implicates extracellular fibrillin assemblies (microfibrils and elastic fibers) in imparting cont